Long-Evans Rat | Charles River - Charles River Laboratories
WEBCharles River provides research animal models, including Long-Evans rats, for use in basic research and nonclinical drug discovery and development.
Laboratory rat - Wikipedia
WEBThe Long–Evans rat is an outbred rat developed by Long and Evans in 1915 by crossbreeding several Wistar females with a wild gray male. Long-Evans rats are white with a black hood, or occasionally white with a brown hood.
Unveiling The Enigmatic Long Evans Rats: A Comprehensive …
WEBAug 9, 2024 · Long Evans rats, renowned for their exceptional qualities, are a breed with a rich history and significant contributions to scientific research. Originating from the efforts of Dr. Herbert McLean Evans, these medium-sized rats exhibit a …
Male long-Evans rats: An outbred model of marked hypothalamic …
WEBJun 17, 2021 · Long-Evans (LE) rats show greater HPA response to stressors than other strains. •. CRH expression in critical brain areas is greater in LE than Sprague-Dawley (SD) rats. •. Glucocorticoid receptor expression was lower in the hippocampal formation of LE rats. •. LE rats are more active in novel environments but showed more passive coping.
Long Evans Rat - an overview | ScienceDirect Topics
WEBThe Long Evans rat is commonly used in alcohol research because this strain drinks alcohol at a higher rate than many other strains (e.g., Wistar or Sprague-Dawley).
Long Evans Rat - an overview | ScienceDirect Topics
WEBThe Long–Evans rat was derived by Joseph Long in 1915 by mating the original Wistar rats with a wild Norway male caught in Berkeley, CA, and subsequent inbreeding of the progeny at the Netherlands Cancer Institute before being transferred back to the National Institutes of Health at Bethesda, MD, in 1973.
Comprehensive Behavioural Analysis of Long Evans and Sprague …
WEBMar 26, 2014 · Long Evans rats required fewer sessions than Sprague Dawley rats to learn operant tasks, including a signal detection task and reversal learning. Furthermore, Long Evans rats housed in enriched cages acquired simple operant tasks faster than standard housed Long Evans rats.
Comprehensive Behavioural Analysis of Long Evans and Sprague …
WEBMar 26, 2014 · Selective strain and housing effects were observed on a number of tests. These included increased locomotion and reduced pre-pulse inhibition in Long Evans rats compared to Sprague Dawley rats; and rats housed in enriched cages had reduced anxiety-like behaviour compared to standard housed rats.
Individual Differences in Neurocognitive Aging in Outbred Male …
WEBMale and female aged outbred Long–Evans rats were obtained at 9 months of age as retired breeders from Charles River Laboratories (Raleigh, NC) and housed individually in a vivarium at Johns Hopkins University until behavioral testing at 23–24 months of age.
Long-Evans and Sprague-Dawley rats have similar skilled …
WEBOct 17, 2003 · The most widely used strain for studies of the neural basis of movement is the out bred, pigmented Long-Evans strain, while the most widely used strains for the study of movement impairments in neurological disease are out bred albino rats, including Sprague-Dawley rats.
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