Syracuse is a city in and the county seat of Onondaga County, New York, United States. With a population of 148,620 and a metropolitan area …Syracuse is a city in and the county seat of Onondaga County, New York, United States. With a population of 148,620 and a metropolitan area of 662,057, it is the fifth-most populated city and 13th-most populated municipality in the state of New York.
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