The Atlanta Falcons (3-2) battle the San Francisco 49ers (4-2) on Sunday Night Football at Levi's Stadium. Kickoff in Santa Clara, California, is scheduled for 8:20 p.m. ET (NBC). Let's analyze BetMGM Sportsbook's NFL odds around the Falcons vs. 49ers odds and make our expert NFL picks and predictions for the best bets.

The Falcons and 49ers game will kick off at 8:20 p.m. ET on Sunday, Oct. 19. The San Francisco 49ers vs. Atlanta Falcons game will be broadcast on NBC on Sunday night. Streamers can also catch the game on Peacock or with Fubo, which comes with a free trial.

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Where to watch 49ers vs. Falcons live stream, TV channel, start time for NFL game live and on demand originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here.

The Falcons, led by quarterback Michael Penix, face the 49ers, led by quarterback Mac Jones, on Sunday, Oct. 19, 2025 at Levi’s Stadium in Santa Clara, California.

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Here’s why: The Falcons’ offense, while talented, is predictable. They do a poor job of differentiating their run and pass looks. Combine that with a young, hyper-confident quarterback in Michael Penix who loves to test tight windows on first-read throws, and you have an offense that can be fooled.