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49ers injury history timeline: How health issues with Brock Purdy, Fred Warner and more is a recurring problem
The San Francisco 49ers are one of the NFL's most successful franchises, but they've also been one of the unluckiest. San Francisco's 2025 NFL season continued an alarming trend of years in which the roster was greatly impacted by injuries.
Niners coach Kyle Shanahan said Mac Jones will again step into the starting quarterback role this week against Atlanta, as Brock Purdy's return from a toe ailment will have to wait at least another week.
A new report from an NFL insider indicates that the San Francisco 49ers are interested in potentially acquiring Trey Hendrickson.
Injuries have accumulated quickly for the 49ers. In addition to Bosa and Purdy, star tight end George Kittle (hamstring), wide receiver Jauan Jennings (shoulder, ankle) and left guard Ben Bartch (ankle) have been hampered by injuries.