Heart failure has increasingly been recognized as a complex, metabolism-driven syndrome that extends far beyond traditional models of hemodynamic ...

Despite significant progress in medicinal chemistry and life sciences research, drug discovery and development remain slow and expensive, taking on average approximately 15 years and US$2 billion to ...

Inside a diseased cell, the genes are in chaos. Some are receiving signals to overproduce a protein. Others are reducing activity to abnormal levels. Up is down and down is up. The right molecule ...

Metabolic engineering, critical in modern biotechnology, focuses on employing microbial systems to produce valuable bioactive ...

Enveda Biosciences Inc., a biotechnology company that leverages artificial intelligence to develop new medicines, announced today that it has raised $130 million in new funding to deliver clinical ...

Nilmani Singh, Chemical and Biomolecular Engineering Professor Huimin Zhao, and Yujie Yuan developed the automated platform FAST-NPS to accelerate bioactive natural product discovery. From caffeine to ...

A major step toward simpler drug development has been taken at the University of Gothenburg. In a new study, researchers have developed stable boron-fluorine compounds that make it possible to ...

Scientists at the University of Helsinki have used a screening technology that can test for the antivirulence and antibacterial effect of hundreds of unknown compounds simultaneously, to identify ...

Triterpenoid saponins are key bioactive compounds responsible for the medicinal value of many plants, yet how plants regulate the balance between saponin production and sterol biosynthesis has ...

The process by which fungi synthesize some of their most potent compounds has remained unclear for many years. This is especially true of cyclopentachromone, a key building block in fungal products ...