49ers, Brandon Aiyuk
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After missing the entire 2025 season, San Francisco 49ers wide receiver Brandon Aiyuk's time in the Bay Area is coming to an end.
Six years of Brandon Aiyuk as a 49er featured highlight-reel grabs, touchdowns, a contract holdout, a major injury and final season littered with negative headlines. It is now over, General Manager John Lynch all but confirmed in his end-of-season press conference Wednesday.
While the 49ers eliminate a Brandon Aiyuk 2026 comeback, coach Kyle Shanahan’s immediate focus is on replacing Robert Saleh at defensive coordinator, likely with Gus Bradley.
The 49ers would prefer to get something back for Brandon Aiyuk, and the Titans have now emerged as a potential trade partner.