Researchers have developed a novel rat model that closely replicates the pathological features and physiological changes associated with human chronic obstructive pulmonary disease (COPD)-associated ...

Panelists discuss how the pathophysiology of pulmonary arterial hypertension involves complex mechanisms across multiple genetic and treatment pathways, with over 20 identified genes and four major ...

Pulmonary hypertension (PH) is characterised by pathological elevation of pressure in the pulmonary circulation, driven by endothelial dysfunction, smooth muscle proliferation and inflammatory ...

Pegtarazimod holds promise for effectively treating acute exacerbations of COPD, a major unmet need in COPD treatment.

The lung maintains a delicate balance between coagulation and inflammation to preserve gas exchange and vascular integrity. In response to infection or injury, endothelial cells, platelets and innate ...

First-in-human Phase 1 study in 56 healthy participants demonstrated KIT2014’s safety and tolerabilityKIT2014 is being developed as an inhalation therapy for respiratory diseases including chronic ...

Philadelphia, April 30, 2025 – Researchers have developed a novel rat model that closely replicates the pathological features and physiological changes associated with human chronic obstructive ...