Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, ...

Arteriovenous malformations, a hallmark of hereditary hemorrhagic telangiectasia, may be driven by endothelial cell-cycle acceleration via CDK6, suggesting potential for repurposing CDK6 inhibitors.

An organism grows and repairs its body using a form of cell division known as mitosis. To divide, a cell must replicate the chromosomes, which carry the DNA (the instructions needed to build the body) ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within ...

This video explains the stages of mitosis, contrasts them with meiosis and the creation of haploid gametes, and concludes by ...

Just one enzyme manages the refilling of the cellular soda machine that replicates our genes. PLK-1 initiates a process in two protein groups, leading to creation of new CENP-A proteins. These CENP-A ...

Studies of genetics conducted in yeast cells, human neurons, mice or other model systems often reveal networks of genes that ...

Infertility affects millions of individuals worldwide and is often caused by the absence of functional gametes. In women, age-related decline in oocyte quality and quantity has been recognized as a ...

About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...

The biological research of UC Santa Cruz’s Needhi Bhalla to determine the molecular motions at the heart of heredity has yielded a new discovery: The proper transfer of genetic materials depends on ...