Newborn nerve cells must squeeze through crowded, narrow spaces—through dense tissue, past other cells, and between fibers—to reach the areas where they form neural circuits in the brain cortex. In a ...

Cancer cells often survive treatment by fixing the DNA damage that therapy is meant to cause. Researchers found that UNI418 ...

Migrating newborn neurons suffer routine double-strand DNA breaks from physical stress during brain development.

DNA repair is essential for successful propagation of genetic material and fidelity of transcription. Nucleotide excision repair (NER) is one of the earliest DNA repair mechanisms, functionally ...

Following an injury, such as a traumatic crush injury, the peripheral nervous system is itself often able to effectively regenerate. This regeneration capacity is mainly attributable to the Schwann ...

Similar to the way DNA damage can contribute to human diseases such as cancer, it can also disrupt growth, development and ...

In a recent study published in the journal Nature, researchers found that the recruitment of neurons to memory circuits is preceded by a cascade of molecular events induced during learning, which ...

Bone fracture healing is a dynamic process that relies on coordinated cellular interactions for effective tissue regeneration. We employ optimized spatial transcriptomics to delineate the locations ...

In each cell of your body, DNA is stored in structures called chromosomes. When cells divide, these chromosomes are copied, ...

As muscles age, their cells lose the ability to regenerate and heal after injury. Cornell Engineering researchers have created the most comprehensive portrait to date of how that change, in mice, ...