A large, multi-institution study led by a Brown University physician-scientist could have important implications for the ...

Cancer drug resistance is the devastating reason that treatments fail and cancers metastasize, spreading to distant sites ...

Cells are not immortal, and that is a good thing. After a certain number of divisions, many human cells stop multiplying for ...

PROVIDENCE, R.I. [Brown University] - Interrupting one function of a protein that plays a key role in cell signaling could ...

A research team has discovered when and why inflammatory signaling affects the formation of blood stem cells in embryos, which will benefit efforts to develop lab-grown, patient-derived stem cell ...

Idiopathic pulmonary fibrosis (IPF) is a chronic disease in which healthy lung tissue is gradually replaced by scar tissue.

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Using human iPSC-derived kidney organoids, researchers showed that NPHP1 deficiency triggers abnormal Hippo signaling that ...

A new study demonstrates that replicative senescence depends upon ATM kinase, and that high oxygen generates a hyperactive ...