A new PLOS Genetics study shows that the single-stranded DNA-binding protein RPA forms an essential ternary complex with ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Cell biologists from RIKEN have provided an unprecedented glimpse into the distinctive features of an unusual chromosome—the inactivated X chromosome copy carried by every female cell. The findings ...

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...

We depend on our cells being able to divide and multiply, whether it’s to replace sunburnt skin or replenish our blood supply and recover from injury. Chromosomes, which carry all of our genetic ...

A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates ...

When cells adapt to new challenges, they often do so by reshuffling their genomes on a grand scale. A new study published in ...