Researchers from Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, USA, report a modification wherein replacing the RNA strand of a heteroduplex oligonucleotide with DNA may ...
DNA/DNA double-stranded oligonucleotide is a new concept of oligonucleotide consisting of DNA-based antisense oligonucleotide and DNA-based complementary strand. When α-tocopherol is bound to ...
In the hours after a heart attack, an intravenous dose of the bacterial protein streptokinase can break up blood clots and restore circulation. But it’s not ideal: Like other clot-busting drugs, ...
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