Migrating newborn neurons suffer routine double-strand DNA breaks from physical stress during brain development.
Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...
Salk Institute scientists identify YAF9B as a protein activated by DNA damage, acting like an emergency responder to ...
While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
We developed Paired-Damage-seq to profile oxidative DNA damage and single-stranded DNA damage jointly with gene-expression analysis in single cells. By dissecting cell-type-specific genome ...
Unlike mild DNA damage exposure, DNA damage repair (DDR) is reported to be ineffective in full-grown mammalian oocytes exposed to moderate or severe DNA damage. The underlying mechanisms of this ...
While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
Similar to the way DNA damage can contribute to human diseases such as cancer, it can also disrupt growth, development and ...
Recently, the research team led by Prof. Junjiu Huang from Sun Yat-sen University, in collaboration with Prof. Fenghua Liu’s team at Guangdong Women and Children Hospital, published a study titled ...
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