Single-stranded DNA-binding proteins (SSBs) are central guardians of genome integrity, selectively coating exposed single-stranded DNA (ssDNA) intermediates that arise during replication, ...

Every cell in the body contains essentially the same DNA, yet a brain cell behaves differently from a muscle cell or an ...

Among the toughest animals ever discovered is a creature so small that a dozen could line up across the width of a grain of ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in ...

DNA origami cages constrain individual proteins toward preferred orientations on electrodes, dramatically improving electrical measurement precision and enabling detection of subtle structural changes ...

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA ...