Immunotherapy with immune checkpoint inhibitors has revolutionised cancer treatment by unleashing T-cell responses against tumours, yet it can precipitate immune-related adverse events affecting both ...

The neuromuscular junction is a specialized synapse between motor neurons and the muscle fibre they innervate. In vertebrates, the postsynaptic side is referred to as the endplate and contains a ...

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

The neuromuscular junction—where nerves and muscle fibers meet—is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...