Scientists have uncovered a surprising principle behind the brain's intricate development from a single cell. Researchers ...
An international research team has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin—DNA and proteins—plays a ...
The human brain is a fascinating and complex organ that supports numerous sophisticated behaviors and abilities that are observed in no other animal species. For centuries, scientists have been trying ...
Previous research has found that the human brain reaches maturity sometime in the 20s, but a new study suggests that it never stops developing. Neuroscientists at the University of Cambridge have ...
Human brain organoids are self-organized three-dimensional (3D) structures that can be derived from induced pluripotent stem cells (iPSC) or embryonic stem cells, similar to the developing brain 1,2,3 ...
In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment, and the brain later in life, investigators at Johns Hopkins Medicine and ...
A new study has created a map of DNA modification in two regions of the brain critical to learning, memory and emotional regulation. The map offers a benchmark for ensuring stem cell-based models ...
The perinatal period, encompassing both prenatal and early postnatal stages, is a highly dynamic and foundational phase of brain development. Despite its significance, limited work has tracked brain ...
Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new Yale-led study shows that, early in development, molecular “traffic cops” known ...
The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are ...
The human brain undergoes significant development during the final prenatal months and through the first year of life. And while scientists have begun to map the developmental trajectories of this ...