ETX-19477 is a potent, selective inhibitor of poly (ADP-ribose) glycohydrolase (PARG), an enzyme that plays a role in the DNA ...

Irene Blair was expected to have another six to eight months to live in June, after her pancreatic cancer rapidly advanced to ...

Exposure to TNF inhibitors during pregnancy and postpartum was not associated with a significantly increased risk for serious infection.

Switching to a second TNF inhibitor in inflammatory bowel disease may raise the risk for immune-mediated inflammatory ...

The optimal approach to treatment in the post-CDK4/6 inhibitor setting remains undefined, but multiple strategies have ...

Stanford scientists discover how blocking 15-PGDH protein regenerates knee cartilage in mice and human tissue, offering hope ...

The new Phase III study will test calderasib in a chemo-free regimen for G12C-mutated patients regardless of PD-L1 status.

Immune checkpoint molecules play a crucial role in keeping the immune system in balance and preventing an attack on the ...

Abstract Aromatase inhibitor–induced musculoskeletal symptoms (AIMSS) were first recognized as a distinct entity in 2001, 5 years after the approval of the first aromatase inhibitor, anastrozole.

Of course, they’ll help manage high blood pressure. But your doctor may prescribe an ACE inhibitor for these other heart conditions: Heart failure: They can prevent further weakening of your heart and ...

Cryogenic electron microscopy models of inflammasome rings (center, ring with hooks) and gasdermin pores (bottom right) Cryogenic electron microscopy models of inflammasome rings (center, ring with ...