Evidence from 2 systematic reviews and 4 further randomised controlled trials (RCTs) suggests that botulinum toxin type A injection is less effective than surgery, no better or worse than topical ...

Medical therapy is an established first-line approach for the treatment of patients with chronic anal fissure; however, the efficacy of individual agents versus placebo remains to be proven in this ...

How do you treat a recurrent anal fissure, 6 months after adequate lateral sphincterotomy? The patient is a 65-year-old, markedly obese man with no evidence of inflammatory bowel disease. An anal ...

In many cases, anal fissures can heal fast with the help of nonsurgical treatments, such as dietary changes, over-the-counter stool softeners, and topical creams. However, they may recur if the ...

Treating an anal fissure typically involves practices that help the area heal, like using a sitz bath or taking stool softeners. Other times a doctor may recommend medication or a medical procedure.

How well does botulinum toxin type A injection work? Two reviews looked at a number of different studies of botulinum toxin type A injection when used to treat chronic anal fissure in adults. No ...

An anal fissure is a small tear in the thin, moist tissue (mucosa) that lines the anus. An anal fissure may occur when you pass hard or large stools during a bowel movement. Anal fissures typically ...