Figure 1: Isolation of a Dicer–TRBP-containing complex. Figure 2: The Dicer–TRBP complex processes miRNAs and associates with siRNA to form a ternary complex with Ago2. Figure 4: The Dicer–TRBP ...
In yeast cells, shown here, the Dicer protein protects DNA (bright blue) by helping to resolve conflicts between transcription and replication. If left unchecked, these conflicts can disrupt both ...