Endocrine diseases of any type — not just diabetes — can represent a cardiovascular risk and patients with those disorders should be screened for high cholesterol, according to a new clinical practice ...

Juxtapid has been available to treat adults with homozygous familial hypercholesterolemia (HoFH), a rare genetic disorder that causes extremely high levels of LDL cholesterol.

Researchers have developed a new compound, ZTA-261, that binds to thyroid hormone receptor beta (THR ). THR plays an important role in the regulation of lipid metabolism, which affects lipid levels in ...

Once again, the United States Preventive Services Task Force (USPSTF) has concluded there is not enough evidence to support screening asymptomatic kids and adolescents for lipid disorders. Published ...

Pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) are produced in large quantities locally in the joints and subsequently enter the bloodstream. TNF-α and IL-6 may promote LDL metabolism by ...

High cholesterol, or hypercholesterolemia, affects nearly 1 in 3 American adults—yet it often goes undetected until a serious event like a heart attack or stroke occurs. It's one of the major ...

The FDA on Friday approved chenodiol (Ctexli) for the treatment of cerebrotendinous xanthomatosis (CTX) in adults. Chenodiol -- a naturally occurring human bile acid also known as chenodeoxycholic ...

In a world-first trial, scientists used a one-off CRISPR gene edit to switch off a liver “fat brake” gene, slashing stubborn LDL cholesterol and triglycerides in patients whose levels refused to budge ...

Treatments for high cholesterol stemming from a rare genetic disorder focus on lowering patients’ LDL, or “bad” cholesterol and delaying disease progression. HDL Therapeutics is looking to go further: ...