How are disease-relevant molecules distributed within tissue? What changes occur even before they become visible under the ...
A new research paper was published in Volume 18 of Aging on July 1, 2026, titled "Senescent cells accumulate lipid droplets." ...
Lipid metabolism in the liver encompasses the coordinated processes of fatty acid uptake, synthesis, storage, oxidation and export. Under physiological conditions, circulating free fatty acids are ...
A new tool enables biomedical researchers from around the world to quickly see the connections between lipids and proteins inside cells, thanks to a new initiative led by scientists at Oregon Health & ...
Please provide your email address to receive an email when new articles are posted on . Mirum Pharmaceuticals received first treatment approval for treatment of cerebrotendinous xanthomatosis. Ctexli ...
A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets—a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center ...
The FDA on Friday approved chenodiol (Ctexli) for the treatment of cerebrotendinous xanthomatosis (CTX) in adults. Chenodiol -- a naturally occurring human bile acid also known as chenodeoxycholic ...
Liver diseases are a growing global health and economic challenge. High alcohol consumption, aging, and increased exposure to metabolism-related risk factors may contribute to an increase in mortality ...
The raw material for de novo fatty acid synthesis is acetyl-CoA, which can be obtained via the citrate shuttle pathway or from acetic acid. ACC and FASN catalyze the conversion of acetyl-CoA into ...
This leads to iron overload, which can have serious consequences for organs and joints. In preclinical studies, MHH researchers have already successfully treated this genetic defect using a targeted ...
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