January 18, 2011 — Findings on positron emission tomography (PET) using the radiotracer florbetapir F 18 correlate with the presence and quantity of brain β-amyloid pathology found at autopsy, a new ...

Rather than giving them more gas, can microglia be driven to clear amyloid plaques by letting up on their brakes? Yes, say scientists led by Marco Colonna at Washington University in St. Louis. In the ...

The new understanding of molecular events that drive the various forms of amyloidosis has led to the expansion of therapeutic options to prevent end-stage disease or even offer a cure, which has added ...

Using postmortem human brain tissue, three-dimensional imaging revealed vascular Aβ deposition patterns and a lower density of parenchymal amyloid plaques surrounding Aβ-positive vessels. Smooth ...

Findings showed testing with Elecsys pTau181 helped to rule out Alzheimer pathology with a 97.9% negative predictive value in this early disease-stage population. The Food and Drug Administration (FDA ...

Alzheimer’s disease is the most common cause of dementia. It is associated with the build-up of small protein aggregates in the brain, termed β-amyloid plaques, ultimately leading to brain damage and ...