Homozygous expression of MHC-II alleles that confer susceptibility to type 1 diabetes limits the efficiency of thymic negative selection and allows for CXCR6 + pathogenic clones to orchestrate the ...
Following the twentieth anniversary of the Nobel Prize in Physiology or Medicine being awarded to Zinkernagel and Doherty in 1996 for the landmark discovery of MHC restriction of TCRs, it is pertinent ...
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