YF550-C1, an E3 ligase inhibitor of CBL-B, to demonstrate T cell and NK cell activation and anti-tumor activities in syngeneic and PDX tumor model. This is an ASCO Meeting Abstract from the 2024 ASCO ...

Pancreatic beta cells (β-cells) reside in a cluster of cells in the pancreas known as the islets of Langerhans. Pancreatic β cells are the only cells that produce insulin - a hormone that decreases ...

Platinum nanoelectrodes measure reactive oxygen and nitrogen species emitted at a macrophage phagocytic cup, revealing how lysosomal pH modulates ROS/RNS flux during frustrated phagocytosis of a glass ...

Macrophages are white blood cells that play a key role in helping to protect us against microscopic threats, from infections to cancer. These cells constantly survey the body’s tissues and consume ...

Shanghai and Suzhou, TOKYO--(BUSINESS WIRE)--Elpiscience Biopharma, Ltd. (Chairman and CEO: Darren Ji, MD, Ph.D., “Elpiscience”) and Astellas Pharma Inc. (TSE ...

When cancer cells begin to die within tumors, they expose signals on their surface that indicate they are dying. Macrophages then detect these signals and engage in phagocytosis, where they eat the ...

Survival rarely comes easy when pancreatic ductal adenocarcinoma strikes. Most people learn of it only after it has spread, ...

PALO ALTO, Calif.--(BUSINESS WIRE)--Pheast Therapeutics (“Pheast”), a biotech developing novel macrophage checkpoint therapies to defy cancer, today announced the presentation of new preclinical data ...

SCIENCE CHINA Life Sciences published a research article online by Professor Yanfeng Gao’s team from the School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University. They designed and ...

SHANGHAI and SUZHOU, China and TOKYO, Dec. 28, 2023 /PRNewswire/ -- Elpiscience Biopharma, Ltd. (Chairman and CEO: Darren Ji, MD, Ph.D., "Elpiscience") and Astellas ...