Biomarkers are increasingly used in cancer management, including lung cancer. The use of circulating tumour DNA (ctDNA) detection has attracted significant interest as a non-invasive, highly specific, ...
DNA methylation is important for gene expression and alterations in DNA methylation are involved in the development and progression of cancer and other major diseases. Analysis of DNA methylation ...
Regular screening practices can identify malignant disease at an early stage, which may provide promising therapeutic options for patients, resulting in improved long-term outcomes. However, for some ...
Immunohistochemical and gene expression profiles as predictors of survival in recurrent high-grade glioma treated with intracranial nivolumab, ipilimumab, and ...
Large scale proteomics of circulating extracellular vesicles to reveal novel biomarkers for pancreatic cancer.
The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.
Native Read Sequencing for Methylation Profiling in Cancer and Neurodegenerative Disease Diagnostics
Methylation analysis holds significant promise for clinical diagnostics, yet its use has been limited due to challenges posed by legacy technologies that undermine clinical applicability, such as ...
DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...
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