Idiopathic nephrotic syndrome is the most common disorder of glomerular function in pediatrics. [1] Approximately 40% of children diagnosed with idiopathic nephrotic syndrome will have a relapsing ...

Rituximab vs placebo significantly improved the 49-week relapse-free rate in adults with frequently relapsing or steroid-dependent adult-onset nephrotic syndrome. Adverse events were more common in ...

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein ...

Focal segmental glomerulosclerosis (FSGS), a progressive kidney disease with an estimated global prevalence of 4%, occurs ...

Primary FSGS, often linked with nephrotic syndrome, typically warrants immunosuppressive therapy, while secondary cases may be harmed by such treatment. The findings underscore the importance of ...

Findings showed a greater proportion of patients achieved sustained complete remission with obinutuzumab vs mycophenolate mofetil at week 52. Topline data were announced from a phase 3 study ...

For children with nephrotic syndrome, there was no difference in time to relapse between two commonly used non-steroid immunosuppressive medications, according to an observational study that emulated ...

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and ...