A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...
Northwestern Medicine scientists have discovered new insights into the production and regulation of a class of noncoding RNAs and how alterations in their signatures diversify and modulate the ...
Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of ...
A study has shown that a type of non-coding RNA molecule could play a role in the development of skin diseases—like eczema or psoriasis—and highlights an important molecular mechanism for driving ...
We knew we had something interesting with T3p, a single small RNA found in breast cancer but absent from normal tissue. After being described in 2018, this molecule took our team on a six-year journey ...
The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...
Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...
Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...
Mutations in the tau gene that cause frontotemporal dementia wreak all manner of neuronal havoc, from endolysosomal traffic jams to mitochondrial distress to a standstill in nucleocytoplasmic ...