Patients with cryptogenic stroke or migraine who undergo patent foramen ovale (PFO) closure are at a fourfold increased risk of new-onset A-fib compared with controls, according to a meta-analysis.

Patent foramen ovale (PFO) closure reduced the risk for recurrent ischemic stroke in most young and middle-aged adults with cryptogenic stroke but increased the risk for atrial fibrillation (AF) in a ...

Because the benefits of patent foramen ovale closure were once in question, physicians remain hesitant about its use in clinical practice. Recent data, however, have confirmed the safety and efficacy ...

A patent foramen ovale (PFO) is a hole in the heart that doesn’t close as expected after birth. Before a baby is born, they have a hole between the left and right sides of their heart. This hole, ...

Five-year results from the randomized REDUCE trial show a continued benefit of patent foramen ovale (PFO) closure compared with antiplatelet therapy alone for the prevention of cryptogenic stroke.

Whether closure of a patent foramen ovale reduces the risk of recurrence of ischemic stroke in patients who have had a cryptogenic ischemic stroke is unknown. In a multicenter, randomized, open-label ...

Researchers found closure of patent foramen ovale could result in reduced monthly migraine days. Treatment with patent foramen ovale (PFO) closure could reduce the frequency of headaches and monthly ...

Shown are Kaplan–Meier estimates in the intention-to-treat population. The inset shows the same data on an enlarged y axis. The incidence of serious adverse events was similar in the two trial groups, ...

ATLANTA -- Scenarios for patent foramen ovale (PFO) closure not covered by the pivotal trials were a key subject of guidelines released by the Society for Cardiovascular Angiography and Interventions ...