Protease inhibitors, such as trypsin inhibitor, serum alpha-1 antitrypsin, or liver aprotinin, are a class of proteins that competitively bind and block the catalytic activity of proteolytic enzymes ...

Plasmids have extensive use in basic and applied biology. These small, circular DNA molecules are used by scientists to introduce new genes into a target organism. Well known for their applications in ...

Plasmid DNA isolation is an important technique in molecular biology, however, achieving effective high-throughput automation of this method has proven to be challenging. Analytik Jena and SynbiCITE ...

The plasmids in gut microbiomes have the potential to contribute to the microbiome community, as well as human health and physiology. Nevertheless, this niche remains poorly explored. In general, most ...

Bacteria can pass genetic information among themselves to gain an advantage over competitors in their environment. One of the ways they do this is by transferring conjugative plasmids—mobile, ...

Plasmid DNA (pDNA) is a fundamental starting material for therapeutic development, including for viral vectors, mRNA therapies, and DNA vaccines. Researchers use capture methods such as anion exchange ...

The term “plasmid” was coined by Joshua Lederberg in 1952 to describe extrachromosomal genetic elements observed during studies of bacterial conjugation and antibiotic resistance. Their transformation ...

Scientists have reported large DNA structures in some archaea that defy easy categorization. When the microbiologist Jillian Banfield and her colleagues started combing through samples of mud from ...

Attractive cost of goods gives plasmid DNA commercial path forward and positions Kaneka Eurogentec as the premier supplier for plasmid DNA. Kaneka Eurogentec, an FDA inspected CDMO focused on the ...

WILMINGTON, Mass.--(BUSINESS WIRE)--Charles River Laboratories International, Inc. (NYSE: CRL), today announced a High Quality (HQ) plasmid manufacturing collaboration with Fondazione Telethon. The ...

Molecular biology is an ever-changing field, and most significant developments have happened because of changes in plasmid DNA sequencing. A plasmid, a circular and small double-stranded DNA entity ...