Markus Ralser of Charité – Universitätsmedizin Berlin investigates human proteoform complexity using timsTOF mass ...

Mass spectrometry has evolved into a cornerstone of structural proteomics, offering rapid, sensitive and site-specific insights into protein architecture, interactions and dynamics. By coupling ...

Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are regulated by the organism to control protein ...

Thermo Fisher Scientific Inc., the world leader in serving science, today announced that its strategic collaboration with Precision Health Research, Singapore (PRECISE) and Nanyang Technological ...

A new data-driven technique, called fingerprint mass spectrometry, provides a method for measuring the mass of individual proteins using nanoscale devices. Caltech scientists have developed a method ...

How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details ...

I have completed a master's degree in a science-related graduate school and work as a researcher at a manufacturing company.

Two years ago, Thermo Fisher Scientific introduced the Thermo Scientific Orbitrap Astral MS, and it’s already been used in more than 320 research articles. “That’s incredible adoption,” says Aaron ...

Charité principal investigator Markus Ralser and colleagues discover and map 179,000 plasma proteoforms, revealing a vast molecular landscape for functional proteomics in biomedical research, drug ...