Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are regulated by the organism to control protein ...

Caltech scientists have developed a method driven by machine learning that allows them to accurately measure the mass of individual particles and molecules using complex nanoscale devices. The new ...

Researchers say they have used a high-sensitivity mass spectrometry technique to improve the accuracy of sandwich ELISA. The team, from biopharmaceutical company Regeneron, hopes their work will help ...

Protein biomarker discovery, validation and utilization require technologies that deliver proteome insights with breadth and depth. Liquid chromatography mass spectrometry (LC-MS), the gold-standard ...

Blood plasma is often described as the most information-rich liquid in the human body, a fluid that carries molecular echoes of nearly every organ and every disease process unfolding somewhere in the ...

An illustration of an antibody disrupting the binding between a virus particle and a receptor on the edge of a membrane. A drug (orange) blocks the SARS-CoV-2 virus (gold sphere with white protruding ...

A new method could soon unlock the vast repository of biological information held in the proteins of ancient soft tissues. The findings could open up a new era for palaeobiological discovery. A new ...

A new data-driven technique, called fingerprint mass spectrometry, provides a method for measuring the mass of individual proteins using nanoscale devices. Caltech scientists have developed a method ...