In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Memorial Sloan Kettering Cancer Center researchers have found RNA neoantigen vaccines that generate long-lived, functional CD8 + T cells in patients with pancreatic ductal adenocarcinoma (PDAC), ...

Researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines. RNA-based medicines are one of the most promising ways to fight human disease, as ...

As RNA therapeutics evolve far beyond their vaccine origins, a new generation of scientists and manufacturers is rethinking how to produce these complex medicines safely, efficiently, and at scale.

Researchers are edging closer to something long imagined but never quite within reach: a single vaccine platform that could be adapted to fight many kinds of cancer. Early experiments in animals and ...

The quest for a vaccine against HIV has been going on for about 40 years — almost as long as the virus that causes AIDS has been known to scientists and the public. There has been some progress ...