University of Pennsylvania researchers have discovered a right-handed, antiparallel double-helix inside influenza ribonucleoprotein complexes that slides strand-against-strand as the viral polymerase ...
Sensing changes in ionic current as barcoded DNA translocates through solid-state nanopores allows the study of how nucleotide sequences alter the DNA-binding specificity of the catalytically inactive ...
During viral reproduction, the influenza polymerase (top left, in blue) scans along the ribonucleoprotein helix to produce messenger RNA. Credit: Science Like a camera-shy teenager, influenza’s ...