Small molecule solubility is a critically important property which affects the efficiency, environmental impact, and phase behavior of synthetic processes. Experimental determination of solubility is ...

Accurate prediction of thermodynamic solubility by machine learning remains a challenge. Recent models often display good performances, but their reliability may be deceiving when used prospectively.

With up to 90% of pipeline drugs facing significant solubility challenges, data and predictive tools for preclinical solubility and bioavailability enhancement are becoming increasingly strategic.

Solubility functions by a group of rules that determine how dissolvable a substance (solute) is in solvent and depends entirely on the physical and chemical properties of the solute and solvent. That ...

Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...

Modern methods and modeling offer a better way to understand solubility issues and solve today’s complex formulation challenges. Poor solubility is an ongoing challenge in pharmaceutical development.

A method for increasing solubility (the ability of one substance to dissolve into another), developed by a graduate student has yielded promising commercial benefits for industry, particularly in ...

HELSINKI & CAMBRIDGE, Mass., October 16, 2025--(BUSINESS WIRE)--The Solubility Company, a leader in advanced solubility measurement science, today announced a major expansion of its global strategy.

Solubility rules are your shortcut to knowing whether mixing two solutions will produce a solid precipitate or stay clear. By learning the key 'always soluble' ions and the common exceptions, you can ...

Introduction Have you ever added a spoon of sugar to your tea and wondered why it disappeared? Where did it go? The sugar did not actually disappear—it changed from its solid form into a dissolved ...