Metazoan gene transcription by RNA polymerase II (Pol II) is regulated in the promoter-proximal region. Pol II can undergo termination in the promoter-proximal region but whether this can contribute ...

A study shows that TEAD1 can form both active and inactive condensates. Small condensates at enhancers or promoters promote transcription, whereas large condensates at pericentromeric heterochromatin ...

A research team introduces a new large-scale study on human transcription factors combining two state-of-the art interactomics methods that allow rapid identification of protein-protein interactions ...

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins called transcription factors that bind to DNA and regulate the expression of ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Transcription factors are a class of proteins that interact with DNA to regulate gene expression. They’re also implicated in many cancers. For years, scientists have considered transcription factors ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.

Recently, Professor Chunxiang You from Shandong Agricultural University and her colleagues published a review article entitled Regulation of fleshy fruit ripening: from transcription factors to ...