Immunotherapies against cancer, vaccines against new viruses (or old viruses in new places), and attempts to resolve pathogenic single-cell defects—all are looking to incorporate transfection ...

Transfection is the process of deliberately introducing nucleic acids into cells. Cell transfection is crucial in the fields of T cell and stem cell therapy. However, the existing transfection ...

Established transfection methodology often uses commercial reagents, which must be formed into liposomes in a sequence of about half a dozen steps. The simplified method reported here is a direct ...

Cell culture was first developed by Harrison in 1907. Since then, this technology has been an important part of scientific research, and it is appreciated that in vitro, cell-based assays are crucial ...

Living cells express genes involved in physiological functions like development and metabolism via complex mechanisms. The cell membrane protects the genome from various exogenous molecules. Cell ...

GEN Recently Asked a Number of Experts about the Applicability of Different Technologies and Their Limitations Transfection is the definitive method for deliberately introducing DNA or RNA into cells, ...

Transfection techniques are pivotal advances in molecular biology that allow scientists to reliably introduce DNA, RNA, ribonucleoproteins (RNPs), and other molecules into cells. Several delivery ...

Exosomes are a class of extracellular vesicles capable of carrying drug cargo including nucleic acids across the blood-brain barrier (BBB). Exosomes have potential for the delivery of nucleic acids ...

Are low gene editing efficiency or gene expression levels preventing your research from advancing? Is your transfection method killing your cells? Are you struggling to reproduce your initial results ...

If you work in a lab, whether you are researching the cutting edge of cell and gene therapy development or running a simple molecular binding screen, the chances are you have done some transfection in ...

Hinnah Campwala (left) is a Principal Scientist in the Cell Biology Development Group at Sartorius BioAnalytical Instruments (Michigan, USA). With a background in drug discovery and immune cell ...