Gene expression in eukaryotes is governed not only at the level of transcription but also by tightly regulated steps in the translation of mRNA into protein. Control mechanisms span initiation, ...

Translational control has emerged as a central regulator of oncogenesis, dictating which messenger RNAs are preferentially converted into proteins that drive malignancy. At the core of this process is ...

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor Hirohisa Ohno (Department of Life Science Frontiers at CiRA) recently led a ...