This database is a repository of normal genetic variability, designed to be a tool for researchers who study neurodegenerative disease. It contains whole-exome sequencing results from nearly 500 ...
People with Parkinson’s disease have α-synuclein clumps in the brain, but these aggregates are not the only thing clogging them up. Constipation plagues many PD patients, often decades before motor ...
In amyloid PET, visual and quantitative reads are at odds 6 percent of the time. In some instances, regional accumulation might be to blame. People with discordant scans accumulated amyloid faster ...
If one person is scanned with one tau PET tracer and a second person, somewhere else, with another, can the results be compared? Can studies using different PET tracers be pooled for joint analysis?
Sanders-Brown Center on Aging 800 South Limestone St. Lexington, KY40536-0230 United States Visit Website Contact: Linda J. Van Eldik, Ph.D. Phone: 859-323-6040 Fax: 859-323-2866 E-mail: ...
The center does not accept donations. Collection is limited to participants in longitudinal research projects conducted by the center. Phenotypes collected include Alzheimer's disease, cognitively ...
Contact Information Tugce Munise Satir, Master's, Ph.D. student Gothenburg, Sweden Education ...
This mouse model was developed to investigate the effects of PINK1 deficiency (Kitada et al., 2007). The model involves a germline deletion of exons 4-7 of the endogenous Pink1 gene, creating ...
Eisai and Biogen yesterday announced positive topline results from the Phase 3 Clarity trial of their anti-amyloid antibody lecanemab. The drug slowed decline on the primary endpoint, CDR-SB, by 27 ...
Biogen’s hopes for a quick regulatory approval of its anti-Aβ antibody aducanumab may be dimming. An advisory panel convened by the U.S. Food and Drug Administration was unimpressed by the evidence ...
A top researcher’s fall from grace sends shock waves through the scientific community. Such is the case with neuropathologist Eliezer Masliah, who stands accused of image falsification spanning 26 ...
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