The Buffalo Bills scored 26 straight points and ran over the Pittsburgh Steelers, 26-7. It dropped Pittsburgh, which had climbed into the AFC North lead after the Baltimore Ravens lost on Thanksgiving, out of the top spot in the division and into the No. 9 seed.

It was an unfortunate sequence of events for the Pittsburgh Steelers coming out of the half. On the first play from scrimmage, Aaron Rodgers was sacked for a nine-yard loss, and he lost a fumble, recovered by Bills DT Christian Benford and returned for a 17-yard touchdown.

Week 16 in the NFL features a loaded afternoon slate with 11 games. Featured in the early window, the Tampa Bay Buccaneers and Carolina Panthers fight it out over first place in the NFC South.

Including the playoffs, the 49ers have won seven of the last eight games against the Seahawks. Coach Mike Macdonald has been around for only three of those games; he's 1-2 against

The Seahawks face the 49ers on Saturday with both teams playing for the NFC West and the No. 1 seed. Here's what to know about the game.