Systemic mastocytosis is a rare, incurable disease that affects approximately one in every 10,000 people. It is a haematological tumor disease, similar to leukemia, in which the bone marrow and other ...

Systemic mastocytosis is a disease where too many abnormal mast cells (a type of white blood cell) build up in your skin and other organs. You might get a variety of symptoms, including itchy skin, ...

Mastocytosis is a rare condition where an excessive amount of mast cells gather in the organs and tissues of the body. It can affect the skin, lymph nodes, bone marrow, and other organ systems. Mast ...

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If you have systemic mastocytosis, your health care provider may recommend a medicine to treat it. One such medicine is Ayvakit (avapritinib), an oral tablet. Systemic mastocytosis is a rare condition ...

Treatment with Ayvakit was associated with promising outcomes in patients with mastocytosis, according to findings from the PIONEER trial. Ayvakit (avapritinib) improved outcomes for patients with non ...

According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...

Systemic mastocytosis is a myeloid neoplasm divided into six subcategories by the recent classification by WHO. It involves the accumulation of abnormal mast cells (MCs) in the skin, liver, spleen, ...