Proceedings of the National Academy of Sciences (PNAS)

Table Of Contents Page, PNAS Volume 123, Number 32

Snakebite maims or kills several hundred thousand people each year. For more than a century, treatment has relied on ...
PNAS

A conserved E3 ubiquitin ligase rewires carotenoid, sterol, and lipid metabolism in Xanthophyllomyces dendrorhous

Eukaryotic cells must balance the biosynthesis of sterols, lipids, and in many organisms, carotenoids, which draw on shared acetyl-CoA-derived precursors. Our study identifies the ubiquitin ligase ...
PNAS

Climatic mechanisms underlying a southwestern French Neanderthal refugium at the onset of the last glaciation

Open in Viewer Climatic configuration of the western European margin mid-latitudes during the MIS 5a/4 transition. (Top) Global and Greenland paleoclimatic records compared to the sea surface ...
PNAS

Dietary DNA in municipal wastewater reveals signatures of wealth, immigration, and coastal proximity

Poor diet is a leading driver of chronic disease worldwide, yet current dietary surveillance methods are costly, slow, and prone to bias. We introduce FoodSeq-FLOW (Food Landscape Observation in ...
PNAS

Journal Club

Journal Club posts are short news stories featuring a recent important, timely journal article selected by one of our Journal Club panelists, who are post-doctoral associates and graduate students in ...
PNAS

High bacterial diversity drives the suppression of a soilborne plant disease

Contributed by James Tiedje; received April 23, 2025; accepted January 26, 2026; reviewed by Gwyn A. Beattie and Corné M. Pieterse Soilborne diseases pose a significant threat to plant health, often ...
PNAS

Deubiquitinase OTULIN dampens RIG-I-dependent antiviral signaling by removing linear ubiquitination from TRAF6

Edited by Adolfo Garcia-Sastre, Icahn School of Medicine at Mount Sinai, New York, NY; received July 3, 2025; accepted January 5, 2026 ...
PNAS

Microheterogeneous singlet oxygen generation at air–water interfaces

Singlet oxygen (1 O 2) drives key photochemical reactions in the atmosphere and natural waters, yet its spatial distribution in multiphase systems remains unexplored. Here, we reveal strong microscale ...
PNAS

Extremism does not stop at borders, and neither should our models

The Democracy Index finding holds up best. Its negative direct effect on offensive VEI (we use β for SDM coefficients throughout) survives spatial adjustment in every bivariate specification (Table 1) ...
PNAS

Anion-mediated solvation structures and intercalation chemistry of aqueous zinc-ion electrolytes

Aqueous zinc-ion batteries (ZIBs) are promising next-generation energy-storage systems owing to their intrinsic safety, low cost, resource abundance, and high-power density. In aqueous ZIBs, ...
PNAS

Social mobilizations for sustainability transformations

Social mobilizations for sustainability transformations Join the global community of subscribers to PNAS, the flagship journal of the US National Academy of Sciences, a mission-driven nonprofit ...
PNAS

Animals that self-medicate

Birds, bees, lizards, elephants, and chimpanzees all share a survival trait: They self-medicate. These animals eat things that make them feel better, or prevent disease, or kill parasites like ...