The San Francisco 49ers have a big decision looming ahead of the Nov. 4 NFL trade deadline after key injuries.

The San Francisco 49ers were dealt another significant injury blow after Sunday's victory over the Atlanta Falcons.

Huff will miss a game or two, while quarterback Brock Purdy is "a reach" to return from his toe injury in Week 8.

San Francisco 49ers pass rusher Bryce Huff had a strip sack, two QB hits and four pressures in Sunday night's win, but is ...

Christian McCaffrey led the San Francisco 49ers to a 20-10 victory over Atlanta with 201 yards from scrimmage and two ...

You would think that the 49ers losing their second-best pass rusher, Bryce Huff, would entice them to make a trade, but it ...

Their ability to maintain a winning record without multiple key impact players on both sides of the ball has shown they have ...

The San Francisco 49ers continue to lose quality players to injury, as cornerback Renardo Green went down against the Atlanta ...

Former 49ers executive Ran Carthon detailed why Fred Warner's injury is a more significant loss for San Francisco than Nick ...

San Francisco 49ers HC Kyle Shanahan gave a major update on the health of Niners ED Bryce Huff after he sustained an injury ...

San Francisco sits at 4-2 but mounting injuries have hurt the team's chances in 2025. Here are five trade targets who could ...

In spite of Bosa's absence for the rest of the year, as well as starting quarterback Brock Purdy and star tight end George ...