Team uses AlphaFold AI to redesign gene-editing proteins to make them safer

A lot of effort has gone into finding ways to minimize or eliminate off-target edits. In a recent issue of Nature, ...

Two ways to read a genome: Body-wide, single-cell atlas maps DNA folding and methylation together

Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells ...

Genome tool places large genetic sequences precisely in rice and tobacco without DNA breaks

Researchers at King Abdullah University of Science and Technology (KAUST) have developed a new way to add large pieces of ...
Frontiers

Volume II: Methods, Tools and Algorithms in Single Cell Bioinformatics

Over the last few years, the single-cell landscape has transitioned from mapping individual cellular transcriptomes to ...