Quarterback Brock Purdy and tight end George Kittle went down with injuries in Week 1 ... QB Trey Lance was placed on season-ending IR with an ankle injury and was replaced by Jimmy Garoppolo.

San Francisco 49ers star George Kittle will likely miss Week 6. His return from a hamstring injury is now a long shot for the upcoming game. Coach Kyl ...

The San Francisco 49ers sit nicely at 3-1 on the season and as they do battle with the Los Angeles Rams on Thursday Night Football, Mac Jones and the offense is cooking the L.A. defense. It would be ...

The 49ers moved to 4-1 with Thursday night's win over the Rams and they're starting to look forward to getting some of their injured players back to help their push for more victories. The wait for ...

The 49ers are undermanned heading into their Week 5 Thursday night clash against the Rams, but they could be getting several key players back for their game next week vs. the Buccaneers. That includes ...

In the 2021 offseason, the Niners decided quarterback Jimmy Garoppolo was not in their long-term plans ... in real time this offseason when the Niners re-signed tight endGeorge Kittle and ...

The San Francisco 49ers bounced back from a Week 4 loss with a win over the Los Angeles Rams on Thursday, despite a flurry of injuries throughout the depth chart. Without starting quarterback Brock ...