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USC Trojans, Notre Dame and college football playoff

Notre Dame vs. USC Prediction, Odds, Picks - October 18, 2025

Preview the Oct. 18 matchup between the Notre Dame Fighting Irish and USC Trojans with predictions, odds, over/under, spread, betting lines and more.

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· 12h · on MSN

Notre Dame’s Playoff Path Could Crumble With a Slip Against USC

Keep an eye on these four standouts when Notre Dame football hosts rival USC

On3 on MSN

USC vs Notre Dame – How to watch, follow, live stream, start time, TV channel

The No. 20 USC Trojans (5-1, 3-1) head back to the Midwest for the third time this season as they meet the No. 13 Notre Dame ...

19h

Trojans Legend Matt Leinart Talks USC-Notre Dame, ‘Bush Push’ Anniversary

The Trojans have struggled in recent years against the rival Fighting Irish, but Matt Leinart thinks his alma mater has ...

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