Why do problems occur with a special variant of 'protein glues', the split inteins, that severely limit their use in producing proteins? A team has now answered this question. Proteins are the ...

Proteins are the building blocks of life. They consist of folded peptide chains, which in turn are made up of a series of amino acids. From stabilizing cell structure to catalyzing chemical reactions, ...

Controlling protein function in mammalian cells could get a little easier. Researchers at Harvard University describe a way to turn on proteins with self-splicing protein domains called inteins.

The SCN1A gene is too large to fit into aconventional viral delivery systems. Scientists overcame this hurdle with a pioneering "split-intein" mechanism, which is like two separate trucks, delivering ...

新型隐球菌被归类为真菌中的关键优先病原体，这突显了迫切需要安全有效的新型抗真菌药物。病原真菌中Prp8蛋白独特的intein自剪接过程使得Prp8 intein成为了一个有吸引力的抗真菌靶点。

Controlling protein function in mammalian cells could get a little easier. Researchers at Harvard University describe a way to turn on proteins with laboratory-evolved self-splicing protein domains ...

Proteins are the building blocks of life. They consist of folded peptide chains, which in turn are made up of a series of amino acids. From stabilising cell structure to catalysing chemical reactions, ...