The San Francisco 49ers are one of the NFL's most successful franchises, but they've also been one of the unluckiest. San Francisco's 2025 NFL season continued an alarming trend of years in which the ...

San Francisco 49ers star George Kittle will likely miss Week 6. His return from a hamstring injury is now a long shot for the upcoming game. Coach Kyl ...

The San Francisco 49ers sit nicely at 3-1 on the season and as they do battle with the Los Angeles Rams on Thursday Night Football, Mac Jones and the offense is cooking the L.A. defense. It would be ...

The 49ers moved to 4-1 with Thursday night's win over the Rams and they're starting to look forward to getting some of their injured players back to help their push for more victories. The wait for ...

The 49ers are undermanned heading into their Week 5 Thursday night clash against the Rams, but they could be getting several key players back for their game next week vs. the Buccaneers. That includes ...

The San Francisco 49ers are down several weapons on offense on Thursday night, including star tight end George Kittle. Kittle, who is currently on short-term injured reserve with a hamstring injury, ...

To replace those departed contributors, the 49ers focused on the 2025 NFL draft and rebuilding their defense. It was a roster reimagining following a similar blueprint of the 2023 Los Angeles Rams and ...