Setmelanotide was associated with significant weight reduction among patients aged 4 years and older with acquired hypothalamic obesity.

Osteoporosis treatment was associated with reduced hospitalization and mortality risks following fragility fracture after 80 years of age.

Hormone therapy as an adjunctive to tirzepatide was associated with greater weight loss than tirzepatide alone among postmenopausal women.

PCOS was associated with an increased risk for vascular events including stroke among women with thrombotic disease, and a lower mean age.

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The FDA has accepted the New Drug Application for ET-600, an oral solution formulation of desmopressin, for the treatment of central diabetes insipidus.

GLP-1 RAs are associated with a modestly increased risk for GERD and gallstone disease but not with GI and biliary complications.

There is increased risk for incident myocardial infarction among adults aged 18 to 64 years with joint exposure to ozone and increased ambient temperature.

Higher UPF-consumption was linked to worse knee OA outcomes among women, including higher pain scores, worse physical function, and thinner knee cartilage.

Compared with those with overweight and normal weight, people with obesity were more likely to report financial hardship and food insecurity.

There has been an increase in certain cardiometabolic risk factors and a decrease in others among adults in the United States in recent years.

There is increased risk for atrial fibrillation in patients with implanted devices exposed to hot outdoor temperatures.