Dilated cardiomyopathy: Pathophysiology and diagnosis
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Dilated cardiomyopathy: Pathophysiology and diagnosis
Sep 12, 2014
Khan AcademyMatthew McPheeters
Ischemic Dilated Cardiomyopathy (IDCM) --- 1. Definition Ischemic dilated cardiomyopathy is left ventricular dilatation and systolic dysfunction caused by coronary artery disease. It results from chronic myocardial ischemia or multiple infarctions leading to loss of viable myocardium, fibrosis, and remodeling. It is the most common cause of systolic heart failure in developed countries. --- 2. Pathophysiology Chronic ischemia or infarction damages the heart muscle, replacing viable tissue with f
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Consequences of IDCMP Ischemic Dilated Cardiomyopathy It’s a form of dilated cardiomyopathy caused by chronic ischemic injury due to coronary artery disease or prior myocardial infarction → resulting in progressive LV dilation, wall thinning, and systolic dysfunction. ---Pathophysiology Overview 1--Coronary artery disease / infarction → loss of viable myocardium 2--Ventricular remodeling → dilation, wall thinning, spherical shape 3--Decreased LV contractility (↓ ejection fraction) 4---Increased
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